En todo el mundo existen al menos 43 ciudades llamadas Santa Cruz. A continuación se encuentra la información geográfica de todas estas ciudades.
| # | País | Región | Ciudad | Coordenadas |
|---|---|---|---|---|
| 1 | Estados Unidos | California | Santa Cruz | 36.974, -122.031 |
| 2 | México | Sonora | Santa Cruz | 31.234, -110.596 |
| 3 | México | Nayarit | Santa Cruz | 21.981, -105.602 |
| 4 | México | Michoacán de Ocampo | Santa Cruz | 19.854, -101.157 |
| 5 | México | San Luis Potosí | Santa Cruz | 23.27, -100.618 |
| 6 | México | Querétaro de Arteaga | Santa Cruz | 20.712, -100.304 |
| 7 | México | México | Santa Cruz | 18.833, -99.983 |
| 8 | México | Hidalgo | Santa Cruz | 21.198, -98.494 |
| 9 | México | Veracruz-Llave | Santa Cruz | 20.796, -98.42 |
| 10 | México | Guerrero | Santa Cruz | 17.533, -98.403 |
| 11 | México | Chiapas | Santa Cruz | 17.809, -93.163 |
| 12 | México | Tabasco | Santa Cruz | 17.418, -91.025 |
| 13 | México | Campeche | Santa Cruz | 20.203, -90.118 |
| 14 | Honduras | Copán | Santa Cruz | 14.75, -88.983 |
| 15 | Honduras | Choluteca | Santa Cruz | 13.258, -87.348 |
| 16 | Honduras | El Paraíso | Santa Cruz | 13.867, -86.633 |
| 17 | Costa Rica | Guanacaste Province | Santa Cruz | 10.261, -85.585 |
| 18 | Panamá | Chiriquí Province | Santa Cruz | 8.235, -81.913 |
| 19 | Perú | Cajamarca | Santa Cruz | -6.095, -78.853 |
| 20 | Jamaica | St. Elizabeth | Santa Cruz | 18.053, -77.698 |
| 21 | Perú | San Martín | Santa Cruz | -6.615, -76.727 |
| 22 | Perú | Lima region | Santa Cruz | -13.078, -76.443 |
| 23 | Perú | Ica | Santa Cruz | -13.832, -76.135 |
| 24 | Perú | Loreto | Santa Cruz | -5.55, -75.8 |
| 25 | Chile | Libertador General Bernardo O'Higgins | Santa Cruz | -34.639, -71.366 |
| 26 | Aruba | Santa Cruz | 12.51, -69.981 | |
| 27 | Venezuela | Estado Aragua | Santa Cruz | 10.18, -67.512 |
| 28 | Brasil | Pernambuco | Santa Cruz | -8.239, -40.332 |
| 29 | Brasil | Río Grande del Norte | Santa Cruz | -6.229, -36.023 |
| 30 | Cabo Verde | Santa Cruz | Santa Cruz | 15.133, -23.567 |
| 31 | Portugal | Madeira | Santa Cruz | 32.688, -16.794 |
| 32 | Portugal | Vila Real | Santa Cruz | 41.76, -7.468 |
| 33 | España | Murcia | Santa Cruz | 38.022, -1.057 |
| 34 | Filipinas | Central Luzon | Santa Cruz | 15.765, 119.909 |
| 35 | Filipinas | Ilocos | Santa Cruz | 17.086, 120.452 |
| 36 | Filipinas | Metro Manila | Santa Cruz | 14.6, 120.983 |
| 37 | Filipinas | Cagayan Valley | Santa Cruz | 18.516, 121.311 |
| 38 | Filipinas | Calabarzon | Santa Cruz | 14.281, 121.416 |
| 39 | Filipinas | Mimaropa | Santa Cruz | 13.476, 122.028 |
| 40 | Filipinas | Western Visayas | Santa Cruz | 10.634, 123.082 |
| 41 | Filipinas | Central Visayas | Santa Cruz | 9.535, 123.105 |
| 42 | Filipinas | Bicol Region | Santa Cruz | 12.876, 124.057 |
| 43 | Filipinas | Davao Region | Santa Cruz | 6.837, 125.413 |